scAtria single-cell spatial atlas resource

BRCA_35063072 · MIBI-TOF / Multiplexed Ion Beam Imaging

BRCA_35063072 · BRCA_35063072__MIBI_TOF

MIBI-TOF / Multiplexed Ion Beam Imaging Spatial proteomics Curated Tiered
Features

Cell-ontology markers

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Features tested
53
Label tier
cell_type_tier_3
Marker output
162 rows
QC
QC passed
Seurat FindAllMarkers, one curated cell-ontology label versus all others. Effect size is logFC; significance is BH FDR.
Cell ontology Feature logFC FDR p value
Granulocyte MPO 8.135 0.00e+0 0.00e+0
Granulocyte MMP9 6.009 0.00e+0 0.00e+0
Granulocyte HIF1a 4.856 0.00e+0 0.00e+0
Granulocyte CD45 2.385 0.00e+0 0.00e+0
Granulocyte GZMB 3.898 4.26e-246 1.18e-246
Granulocyte CD68 2.860 9.16e-173 3.05e-173
Granulocyte CD20 2.747 5.40e-102 2.10e-102
Granulocyte CD11c 2.354 1.18e-52 5.22e-53
Granulocyte CD36 1.865 7.43e-41 3.71e-41
Granulocyte Na 0.268 6.67e-33 3.71e-33
Granulocyte VIM 0.834 1.83e-31 1.12e-31
Granulocyte CD14 1.324 1.43e-16 9.77e-17
Granulocyte CD44 0.527 1.43e-16 1.03e-16
Granulocyte GLUT1 0.514 4.22e-10 3.28e-10
Granulocyte CD31 1.268 3.17e-8 2.65e-8
Granulocyte CD3 0.803 2.41e-5 2.14e-5
Granulocyte FAP 0.614 7.59e-4 7.17e-4
Granulocyte HLADRDPDQ 0.261 4.47e-2 4.47e-2
Mast cell Tryptase 7.418 0.00e+0 0.00e+0
Mast cell VIM 1.651 6.82e-266 1.51e-266
Mast cell CD44 1.368 3.35e-221 1.12e-221
Mast cell GZMB 2.787 4.15e-78 1.84e-78
Mast cell IDO1 1.612 4.95e-66 2.75e-66
Mast cell COLI 1.022 1.25e-45 8.34e-46
Mast cell CD45 0.719 2.15e-32 1.67e-32
Mast cell COX2 1.062 1.73e-26 1.53e-26
Mast cell CD36 0.376 2.54e-3 2.54e-3
B cell CD20 7.102 0.00e+0 0.00e+0
B cell CD45 2.859 0.00e+0 0.00e+0
B cell HLADRDPDQ 2.818 0.00e+0 0.00e+0
B cell CD44 1.322 3.70e-125 6.72e-126
B cell GLUT1 1.263 1.17e-119 2.67e-120
B cell VIM 1.451 1.76e-117 4.81e-118
B cell CD4 2.025 1.44e-104 4.58e-105
B cell Au 0.390 1.97e-104 7.17e-105
B cell Ta 0.509 2.88e-97 1.18e-97
B cell CD3 1.996 9.67e-93 4.40e-93
B cell Ca40 0.304 3.12e-74 1.56e-74
B cell Na 0.270 6.00e-54 3.27e-54
B cell COLI 1.580 6.82e-40 4.03e-40
B cell pS6 0.920 1.46e-37 9.29e-38
B cell CD8 1.645 3.64e-33 2.48e-33
B cell HIF1a 1.294 1.09e-27 7.96e-28
B cell FAP 1.355 5.38e-23 4.16e-23
B cell ECADKRTCD45GLUT1CD44 0.330 7.71e-22 6.31e-22
B cell CD14 0.807 5.09e-19 4.40e-19
B cell CD36 1.119 1.02e-11 9.30e-12
B cell ECADKRTCD45GLUT1 0.314 8.66e-11 8.26e-11
B cell CD68 0.403 5.18e-4 5.18e-4
T cell CD3 5.651 0.00e+0 0.00e+0
T cell CD4 5.252 0.00e+0 0.00e+0
T cell CD8 5.239 0.00e+0 0.00e+0
T cell CD20 3.526 0.00e+0 0.00e+0
T cell CD45 3.183 0.00e+0 0.00e+0
T cell CD11c 2.852 0.00e+0 0.00e+0
T cell HLADRDPDQ 2.134 0.00e+0 0.00e+0
T cell VIM 1.699 0.00e+0 0.00e+0
T cell CD44 1.467 0.00e+0 0.00e+0
T cell GLUT1 1.073 0.00e+0 0.00e+0
T cell CD14 1.642 5.61e-292 2.47e-292
T cell COLI 1.294 4.16e-228 2.00e-228
T cell HIF1a 1.525 2.23e-225 1.16e-225
T cell ECADKRTCD45GLUT1CD44 0.383 5.71e-192 3.20e-192
T cell FAP 1.569 1.61e-189 9.64e-190
T cell Ta 0.293 1.25e-170 8.03e-171
T cell CD68 1.451 1.32e-153 8.95e-154
T cell MMP9 1.693 7.54e-136 5.43e-136
T cell PDL1 1.541 1.32e-97 1.01e-97
T cell ECADKRTCD45GLUT1 0.357 7.92e-94 6.34e-94
T cell ECADKRTCD45 0.343 5.15e-52 4.32e-52
T cell CD31 0.739 6.81e-43 5.99e-43
T cell CD36 0.833 7.55e-43 6.95e-43
T cell pS6 0.275 1.06e-17 1.02e-17
T cell IDO1 0.443 1.90e-9 1.90e-9
Endothelial cell CD31 5.530 0.00e+0 0.00e+0
Endothelial cell CD36 2.922 0.00e+0 0.00e+0
Endothelial cell VIM 1.906 0.00e+0 0.00e+0
Endothelial cell SMA 1.730 0.00e+0 0.00e+0
Endothelial cell COLI 1.337 1.04e-289 8.63e-290
Endothelial cell FAP 1.170 2.55e-73 2.55e-73
Macrophage CD68 4.918 0.00e+0 0.00e+0
Macrophage PD1 4.355 0.00e+0 0.00e+0
Macrophage MMP9 3.492 0.00e+0 0.00e+0
Macrophage CD4 2.730 0.00e+0 0.00e+0
Macrophage HLADRDPDQ 2.352 0.00e+0 0.00e+0
Macrophage CD45 2.153 0.00e+0 0.00e+0
Macrophage CD11c 2.859 3.66e-297 1.17e-297
Macrophage VIM 1.359 2.37e-224 8.60e-225
Macrophage Background 0.347 2.18e-116 8.91e-117
Macrophage CD14 1.631 1.66e-107 7.54e-108
Macrophage CD3 1.759 2.81e-107 1.40e-107
Macrophage GLUT1 0.811 5.00e-90 2.73e-90
Macrophage COLI 1.208 8.86e-81 5.24e-81
Macrophage CD36 1.592 2.56e-73 1.63e-73
Macrophage CD44 0.733 6.33e-69 4.32e-69
Macrophage HIF1a 1.440 1.06e-57 7.71e-58
Macrophage PDL1 1.619 1.34e-55 1.04e-55
Macrophage CD8 1.482 3.51e-47 2.87e-47
Macrophage CD31 0.863 1.56e-21 1.35e-21
Macrophage FAP 0.869 2.27e-19 2.07e-19
Macrophage IDO1 1.075 2.68e-17 2.56e-17
Macrophage pS6 0.481 5.69e-11 5.69e-11
Monocyte CD14 3.785 0.00e+0 0.00e+0
Monocyte HLADRDPDQ 2.045 0.00e+0 0.00e+0
Monocyte CD45 1.808 0.00e+0 0.00e+0
Monocyte VIM 1.097 7.56e-307 2.75e-307
Monocyte COLI 1.234 1.09e-169 4.93e-170
Monocyte CD36 1.741 3.20e-158 1.75e-158
Monocyte HIF1a 1.342 8.72e-107 5.55e-107
Monocyte CD68 0.692 1.09e-41 7.94e-42
Monocyte FAP 0.658 3.28e-19 2.69e-19
Monocyte pS6 0.361 1.63e-15 1.49e-15
Monocyte CD44 0.259 2.08e-14 2.08e-14
Dendritic cell CD11c 3.623 0.00e+0 0.00e+0
Dendritic cell HLADRDPDQ 2.978 0.00e+0 0.00e+0
Dendritic cell CD45 2.078 0.00e+0 0.00e+0
Dendritic cell COLI 1.650 0.00e+0 0.00e+0
Dendritic cell VIM 1.193 0.00e+0 0.00e+0
Dendritic cell CD4 1.971 4.07e-272 1.63e-272
Dendritic cell Ta 0.300 7.36e-175 3.44e-175
Dendritic cell CD68 1.369 1.73e-96 9.21e-97
Dendritic cell HIF1a 1.091 2.09e-53 1.25e-53
Dendritic cell FAP 0.822 5.67e-43 3.78e-43
Dendritic cell CD14 1.142 4.71e-42 3.46e-42
Dendritic cell GLUT1 0.419 7.63e-37 6.10e-37
Dendritic cell CD44 0.396 2.36e-29 2.05e-29
Dendritic cell pS6 0.454 1.99e-19 1.86e-19
Dendritic cell CD36 0.370 1.23e-7 1.23e-7
Myoepithelial cell SMA 3.122 0.00e+0 0.00e+0
Myoepithelial cell P63 2.960 0.00e+0 0.00e+0
Myoepithelial cell CK5norm 2.539 0.00e+0 0.00e+0
Myoepithelial cell CK5 1.949 0.00e+0 0.00e+0
Myoepithelial cell ECAD 0.494 4.39e-162 3.13e-162
Myoepithelial cell HER2 0.461 1.06e-60 9.05e-61
Myoepithelial cell IDO1 0.358 1.83e-18 1.83e-18
Tumor/Malignant cell ER 2.811 0.00e+0 0.00e+0
Tumor/Malignant cell PanKRT 2.530 0.00e+0 0.00e+0
Tumor/Malignant cell CK7 2.490 0.00e+0 0.00e+0
Tumor/Malignant cell ECADKRT 2.349 0.00e+0 0.00e+0
Tumor/Malignant cell ECAD 2.158 0.00e+0 0.00e+0
Tumor/Malignant cell HER2 2.060 0.00e+0 0.00e+0
Tumor/Malignant cell Ki67 1.705 0.00e+0 0.00e+0
Tumor/Malignant cell ECADKRTCD45 1.333 0.00e+0 0.00e+0
Tumor/Malignant cell COX2 1.261 0.00e+0 0.00e+0
Tumor/Malignant cell ECADKRTCD45GLUT1 1.102 0.00e+0 0.00e+0
Tumor/Malignant cell ECADKRTCD45GLUT1CD44 0.863 0.00e+0 0.00e+0
Tumor/Malignant cell GLUT1 0.312 2.36e-278 1.89e-278
Tumor/Malignant cell CK5 0.619 6.43e-259 5.57e-259
Tumor/Malignant cell IDO1 0.916 1.24e-207 1.15e-207
Tumor/Malignant cell pS6 0.481 2.05e-186 2.05e-186
Immune cell, unspecified CD45 2.457 0.00e+0 0.00e+0
Immune cell, unspecified MMP9 2.905 1.61e-81 5.38e-82
Immune cell, unspecified Ta 0.284 2.17e-62 1.08e-62
Immune cell, unspecified HIF1a 1.892 5.61e-26 3.74e-26
Immune cell, unspecified VIM 0.337 3.28e-16 2.74e-16
Immune cell, unspecified COLI 0.529 4.03e-12 4.03e-12
Fibroblast FAP 2.246 0.00e+0 0.00e+0
Fibroblast VIM 1.809 0.00e+0 0.00e+0
Fibroblast COLI 1.800 0.00e+0 0.00e+0
Fibroblast Ta 0.296 0.00e+0 0.00e+0
Fibroblast CD36 1.616 1.47e-215 1.22e-215
Fibroblast SMA 0.833 3.42e-163 3.42e-163