scAtria single-cell spatial atlas resource

BoneMarrow_38714197 · PCF / CODEX / PhenoCycler Fusion

BoneMarrow_38714197 · BoneMarrow_38714197__PCF_CODEX

PCF / CODEX / PhenoCycler Fusion Spatial proteomics Curated Tiered
Features

Cell-ontology markers

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Features tested
52
Label tier
cell_type_tier_3
Marker output
213 rows
QC
Protein panel
Seurat FindAllMarkers, one curated cell-ontology label versus all others. Effect size is logFC; significance is BH FDR.
Cell ontology Feature logFC FDR p value
Fibroblast HLA.DR 11.316 0.00e+0 0.00e+0
Fibroblast CD56 2.568 3.19e-74 7.09e-75
Fibroblast PDPN 3.678 1.90e-40 6.33e-41
Fibroblast CD44 4.273 8.09e-33 3.60e-33
Fibroblast TGFB1 0.806 2.55e-9 1.41e-9
Fibroblast BCL2 0.771 7.18e-9 4.79e-9
Fibroblast CD14 0.386 6.61e-3 5.14e-3
Fibroblast CD34 0.519 8.09e-3 7.19e-3
Fibroblast MastCellTryptase 0.943 2.03e-2 2.03e-2
Megakaryocyte CD61 3.564 0.00e+0 0.00e+0
Megakaryocyte TGFB1 2.359 0.00e+0 0.00e+0
Megakaryocyte FOXC1 2.232 0.00e+0 0.00e+0
Megakaryocyte CD49F 1.662 0.00e+0 0.00e+0
Megakaryocyte GATA1 1.487 0.00e+0 0.00e+0
Megakaryocyte CD34 0.761 0.00e+0 0.00e+0
Megakaryocyte CD71 0.561 0.00e+0 0.00e+0
Megakaryocyte PAX5 0.272 0.00e+0 0.00e+0
Megakaryocyte OXPHOS 0.299 8.84e-248 7.96e-248
Megakaryocyte CXCR4 0.299 1.28e-132 1.28e-132
Pericyte/Smooth muscle ASMA 3.520 0.00e+0 0.00e+0
Pericyte/Smooth muscle CD146 2.096 0.00e+0 0.00e+0
Pericyte/Smooth muscle VIM 0.975 0.00e+0 0.00e+0
Pericyte/Smooth muscle CD49F 0.713 0.00e+0 0.00e+0
Pericyte/Smooth muscle CXCL12 0.483 0.00e+0 0.00e+0
Pericyte/Smooth muscle BCL2 0.345 0.00e+0 0.00e+0
Pericyte/Smooth muscle CD90 0.674 4.35e-200 3.04e-200
Pericyte/Smooth muscle CD14 0.377 2.09e-163 1.67e-163
Pericyte/Smooth muscle CD271 0.478 2.85e-161 2.57e-161
Pericyte/Smooth muscle HLA-DR 0.389 3.04e-47 3.04e-47
Other MastCellTryptase 3.403 0.00e+0 0.00e+0
Other CD79A 1.982 0.00e+0 0.00e+0
Other CD90 1.720 0.00e+0 0.00e+0
Other FOXC1 1.614 0.00e+0 0.00e+0
Other PDPN 1.343 0.00e+0 0.00e+0
Other SPINK2 0.849 0.00e+0 0.00e+0
Other CD117 0.820 0.00e+0 0.00e+0
Other CXCR4 0.756 0.00e+0 0.00e+0
Other TGFB1 0.664 0.00e+0 0.00e+0
Other CD271 0.579 0.00e+0 0.00e+0
Other CD61 0.489 0.00e+0 0.00e+0
Other CD19 0.448 0.00e+0 0.00e+0
Other GATA1 0.401 0.00e+0 0.00e+0
Other CD45RA 0.342 0.00e+0 0.00e+0
Other CD49F 0.329 0.00e+0 0.00e+0
Other CD11C 0.304 0.00e+0 0.00e+0
Other BCAT 0.251 0.00e+0 0.00e+0
Other CD123 0.321 5.83e-109 5.83e-109
Tumor/Malignant cell CD56 3.066 0.00e+0 0.00e+0
Tumor/Malignant cell NPM1C 2.571 0.00e+0 0.00e+0
Tumor/Malignant cell SPINK2 0.625 0.00e+0 0.00e+0
Tumor/Malignant cell CD90 0.490 0.00e+0 0.00e+0
Tumor/Malignant cell CD49F 0.335 0.00e+0 0.00e+0
Tumor/Malignant cell MPO 0.264 0.00e+0 0.00e+0
Tumor/Malignant cell OXPHOS 0.259 0.00e+0 0.00e+0
Erythroid progenitor cell CD34 2.984 0.00e+0 0.00e+0
Erythroid progenitor cell SPINK2 1.641 5.38e-222 6.33e-223
Erythroid progenitor cell GATA1 0.472 4.15e-214 7.33e-215
Erythroid progenitor cell PDPN 0.702 3.36e-158 7.92e-159
Erythroid progenitor cell PAX5 0.416 4.24e-127 1.25e-127
Erythroid progenitor cell PLP1 0.511 5.30e-125 1.87e-125
Erythroid progenitor cell BCAT 0.592 2.96e-108 1.22e-108
Erythroid progenitor cell CD19 0.706 5.65e-107 2.66e-107
Erythroid progenitor cell MastCellTryptase 0.616 3.17e-96 1.68e-96
Erythroid progenitor cell CD44 0.881 1.18e-94 6.95e-95
Erythroid progenitor cell CXCR4 0.348 3.56e-77 2.30e-77
Erythroid progenitor cell FOXC1 0.549 1.37e-76 9.67e-77
Erythroid progenitor cell OXPHOS 0.337 3.14e-70 2.40e-70
Erythroid progenitor cell CD71 0.275 4.74e-69 3.90e-69
Erythroid progenitor cell CD10 0.388 1.69e-61 1.49e-61
Erythroid progenitor cell GYPC 0.277 2.50e-39 2.35e-39
Erythroid progenitor cell CD123 0.317 1.35e-17 1.35e-17
Hematopoietic stem/progenitor cell CD34 2.771 0.00e+0 0.00e+0
Hematopoietic stem/progenitor cell CD44 1.474 0.00e+0 0.00e+0
Hematopoietic stem/progenitor cell SPINK2 1.149 0.00e+0 0.00e+0
Hematopoietic stem/progenitor cell PDPN 0.459 0.00e+0 0.00e+0
B cell CD79A 2.706 0.00e+0 0.00e+0
B cell PAX5 1.764 0.00e+0 0.00e+0
B cell HLA-DR 1.094 0.00e+0 0.00e+0
B cell CD45RA 1.051 0.00e+0 0.00e+0
B cell CD19 0.630 0.00e+0 0.00e+0
B cell CD117 0.576 0.00e+0 0.00e+0
B cell BCL2 0.449 0.00e+0 0.00e+0
B cell CD44 0.274 0.00e+0 0.00e+0
Endothelial cell CD34 2.555 0.00e+0 0.00e+0
Endothelial cell VECAD 1.428 0.00e+0 0.00e+0
Endothelial cell CD146 1.097 0.00e+0 0.00e+0
Endothelial cell CD49F 0.815 0.00e+0 0.00e+0
Endothelial cell BCAT 0.779 0.00e+0 0.00e+0
Endothelial cell VIM 0.705 0.00e+0 0.00e+0
Endothelial cell ASMA 0.592 0.00e+0 0.00e+0
Endothelial cell CD90 0.571 0.00e+0 0.00e+0
Endothelial cell CD4 0.299 0.00e+0 0.00e+0
Endothelial cell CD14 0.293 0.00e+0 0.00e+0
Endothelial cell CD271 0.292 0.00e+0 0.00e+0
Endothelial cell PDPN 0.253 0.00e+0 0.00e+0
Endothelial cell CXCL12 0.390 1.92e-244 1.78e-244
Endothelial cell CD56 0.450 7.99e-123 7.99e-123
T cell CD8 2.483 0.00e+0 0.00e+0
T cell CD3e 2.142 0.00e+0 0.00e+0
T cell BCL2 1.306 0.00e+0 0.00e+0
T cell CD44 1.208 0.00e+0 0.00e+0
T cell CD4 1.165 0.00e+0 0.00e+0
T cell CD117 1.072 0.00e+0 0.00e+0
T cell CD45 1.064 0.00e+0 0.00e+0
T cell CXCR4 0.643 0.00e+0 0.00e+0
T cell CD19 0.588 0.00e+0 0.00e+0
T cell CD45RA 0.412 0.00e+0 0.00e+0
T cell CXCL12 0.319 0.00e+0 0.00e+0
Mesenchymal stromal cell CD90 1.949 0.00e+0 0.00e+0
Mesenchymal stromal cell FOXC1 1.863 0.00e+0 0.00e+0
Mesenchymal stromal cell VIM 1.733 0.00e+0 0.00e+0
Mesenchymal stromal cell CXCL12 1.416 0.00e+0 0.00e+0
Mesenchymal stromal cell CD49F 1.154 0.00e+0 0.00e+0
Mesenchymal stromal cell CD271 0.998 0.00e+0 0.00e+0
Mesenchymal stromal cell VCAM1 0.777 0.00e+0 0.00e+0
Mesenchymal stromal cell BCAT 0.437 0.00e+0 0.00e+0
Mesenchymal stromal cell CD146 0.418 0.00e+0 0.00e+0
Mesenchymal stromal cell CD14 0.286 0.00e+0 0.00e+0
Mesenchymal stromal cell CD56 0.412 1.69e-3 1.69e-3
Plasma cell CD38 1.925 0.00e+0 0.00e+0
Plasma cell CD79A 1.889 0.00e+0 0.00e+0
Plasma cell CD11B 1.061 0.00e+0 0.00e+0
Plasma cell BCL2 0.949 0.00e+0 0.00e+0
Plasma cell CD33 0.737 0.00e+0 0.00e+0
Plasma cell CD34 0.729 0.00e+0 0.00e+0
Plasma cell CD56 0.684 0.00e+0 0.00e+0
Plasma cell CD90 0.604 0.00e+0 0.00e+0
Plasma cell VIM 0.520 0.00e+0 0.00e+0
Plasma cell OXPHOS 0.454 0.00e+0 0.00e+0
Plasma cell CD138 0.412 0.00e+0 0.00e+0
Plasma cell CD49F 0.387 0.00e+0 0.00e+0
Plasma cell CXCL12 0.334 0.00e+0 0.00e+0
Plasma cell CD117 0.277 0.00e+0 0.00e+0
Plasma cell CD146 0.270 0.00e+0 0.00e+0
Plasma cell PLP1 0.259 0.00e+0 0.00e+0
Plasma cell NPM1C 0.542 1.14e-261 1.14e-261
Macrophage CD163 1.514 0.00e+0 0.00e+0
Macrophage VCAM1 0.968 0.00e+0 0.00e+0
Macrophage CD68 0.744 0.00e+0 0.00e+0
Macrophage CD4 0.565 0.00e+0 0.00e+0
Macrophage CD11C 0.527 0.00e+0 0.00e+0
Macrophage HLA-DR 0.348 0.00e+0 0.00e+0
Macrophage VIM 0.272 0.00e+0 0.00e+0
Dendritic cell CD123 1.501 0.00e+0 0.00e+0
Dendritic cell CD56 1.008 0.00e+0 0.00e+0
Dendritic cell CD45RA 0.922 0.00e+0 0.00e+0
Dendritic cell CD44 0.681 0.00e+0 0.00e+0
Dendritic cell CD4 0.402 0.00e+0 0.00e+0
Dendritic cell BCL2 0.290 0.00e+0 0.00e+0
Dendritic cell NPM1C 0.414 4.34e-177 3.80e-177
Dendritic cell SPINK2 0.392 3.24e-88 3.24e-88
Monocyte CD14 1.485 0.00e+0 0.00e+0
Monocyte CD11C 1.170 0.00e+0 0.00e+0
Monocyte HLA-DR 0.946 0.00e+0 0.00e+0
Monocyte CD44 0.737 0.00e+0 0.00e+0
Monocyte CD45 0.720 0.00e+0 0.00e+0
Monocyte CD49F 0.571 0.00e+0 0.00e+0
Monocyte VIM 0.541 0.00e+0 0.00e+0
Monocyte CD56 0.504 0.00e+0 0.00e+0
Monocyte CD45RA 0.434 0.00e+0 0.00e+0
Monocyte CD117 0.405 0.00e+0 0.00e+0
Monocyte CXCL12 0.382 0.00e+0 0.00e+0
Monocyte CD11B 0.298 0.00e+0 0.00e+0
Monocyte CD68 0.288 0.00e+0 0.00e+0
Monocyte CD123 0.280 0.00e+0 0.00e+0
Monocyte BCL2 0.275 0.00e+0 0.00e+0
Myeloid cell, unspecified CD15 1.476 0.00e+0 0.00e+0
Myeloid cell, unspecified HIF1A 1.375 0.00e+0 0.00e+0
Myeloid cell, unspecified CD141 1.192 0.00e+0 0.00e+0
Myeloid cell, unspecified MPO 1.147 0.00e+0 0.00e+0
Myeloid cell, unspecified VECAD 0.847 0.00e+0 0.00e+0
Myeloid cell, unspecified CD33 0.666 0.00e+0 0.00e+0
Myeloid cell, unspecified CD11B 0.354 0.00e+0 0.00e+0
Myeloid cell, unspecified CD68 0.335 0.00e+0 0.00e+0
Bone-forming stromal cell VIM 1.459 0.00e+0 0.00e+0
Bone-forming stromal cell CD271 1.292 0.00e+0 0.00e+0
Bone-forming stromal cell CD90 1.099 0.00e+0 0.00e+0
Bone-forming stromal cell BCAT 0.799 0.00e+0 0.00e+0
Bone-forming stromal cell ASMA 0.749 0.00e+0 0.00e+0
Bone-forming stromal cell CD49F 0.738 0.00e+0 0.00e+0
Bone-forming stromal cell CXCL12 0.708 0.00e+0 0.00e+0
Bone-forming stromal cell CD138 0.663 0.00e+0 0.00e+0
Bone-forming stromal cell CD14 0.497 0.00e+0 0.00e+0
Bone-forming stromal cell CD71 0.368 1.87e-182 1.70e-182
Bone-forming stromal cell CD56 2.485 7.65e-7 7.65e-7
Adipocyte CD146 1.007 0.00e+0 0.00e+0
Adipocyte VIM 0.675 0.00e+0 0.00e+0
Adipocyte CD271 0.454 0.00e+0 0.00e+0
Adipocyte CXCL12 0.343 0.00e+0 0.00e+0
Adipocyte FOXC1 1.101 2.07e-99 1.73e-99
Adipocyte CD56 0.325 1.25e-8 1.25e-8
Erythroid cell GYPC 0.804 0.00e+0 0.00e+0
Erythroid cell GATA1 0.770 0.00e+0 0.00e+0
Erythroid cell BCAT 0.732 0.00e+0 0.00e+0
Erythroid cell CD10 0.687 0.00e+0 0.00e+0
Erythroid cell VCAM1 0.671 0.00e+0 0.00e+0
Erythroid cell CD71 0.506 0.00e+0 0.00e+0
Erythroid cell FOXC1 0.447 0.00e+0 0.00e+0
Erythroid cell SPINK2 0.444 0.00e+0 0.00e+0
Erythroid cell CD163 0.437 0.00e+0 0.00e+0
Erythroid cell CXCR4 0.315 0.00e+0 0.00e+0
Glial cell PLP1 1.337 1.79e-33 1.49e-34
Glial cell CD146 2.533 6.95e-33 1.16e-33
Glial cell CD49F 2.069 3.64e-29 9.09e-30
Glial cell VIM 1.738 3.96e-29 1.32e-29
Glial cell CXCL12 1.299 1.34e-25 5.60e-26
Glial cell CD271 2.603 6.78e-21 3.39e-21
Glial cell BCAT 1.348 9.87e-20 5.76e-20
Glial cell CD90 1.906 1.19e-18 7.95e-19
Glial cell BCL2 0.703 1.74e-18 1.30e-18
Glial cell CD14 0.593 2.73e-18 2.27e-18
Glial cell ASMA 2.272 5.42e-15 4.97e-15
Glial cell CD34 1.687 2.60e-2 2.60e-2