HGSC_39179931 · CosMx SMI / NanoString SMI

HGSC_39179931 · HGSC_39179931__CosMx_SMI

CosMx SMI / NanoString SMI Spatial transcriptomics Curated Tiered
Features

Cell-ontology markers

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Features tested
6,297
Label tier
cell_type_tier_3
Marker output
1,712 rows
QC
QC passed
Seurat FindAllMarkers, one curated cell-ontology label versus all others. Effect size is logFC; significance is BH FDR.
Cell ontology Feature logFC FDR p value
B cell IGHG2 6.096 0.00e+0 0.00e+0
B cell JCHAIN 5.943 0.00e+0 0.00e+0
B cell IGHG1 5.848 0.00e+0 0.00e+0
B cell IGHA1 5.772 0.00e+0 0.00e+0
B cell IGHM 5.279 0.00e+0 0.00e+0
B cell MZB1 5.229 0.00e+0 0.00e+0
B cell IGKC 5.173 0.00e+0 0.00e+0
B cell FAM30A 3.852 0.00e+0 0.00e+0
B cell XBP1 2.975 0.00e+0 0.00e+0
B cell IRF4 2.904 0.00e+0 0.00e+0
B cell CD38 2.888 0.00e+0 0.00e+0
B cell CD79A 2.697 0.00e+0 0.00e+0
B cell LPAR5 2.676 0.00e+0 0.00e+0
B cell EGF 2.555 0.00e+0 0.00e+0
B cell MPO 2.023 0.00e+0 0.00e+0
B cell CD27 1.657 0.00e+0 0.00e+0
B cell FKBP11 1.594 0.00e+0 0.00e+0
B cell RGS1 1.586 0.00e+0 0.00e+0
B cell CSF2RB 1.582 0.00e+0 0.00e+0
B cell CCR5 1.571 0.00e+0 0.00e+0
B cell CCR2 1.556 0.00e+0 0.00e+0
B cell CASP3 1.464 0.00e+0 0.00e+0
B cell DUSP5 1.457 0.00e+0 0.00e+0
B cell TNFRSF17 1.430 0.00e+0 0.00e+0
B cell BTK 1.221 0.00e+0 0.00e+0
Endothelial cell VWF 5.442 0.00e+0 0.00e+0
Endothelial cell FLT1 4.900 0.00e+0 0.00e+0
Endothelial cell COL4A1 4.369 0.00e+0 0.00e+0
Endothelial cell IGFBP3 4.098 0.00e+0 0.00e+0
Endothelial cell CLEC14A 4.058 0.00e+0 0.00e+0
Endothelial cell CD93 4.009 0.00e+0 0.00e+0
Endothelial cell CD34 3.990 0.00e+0 0.00e+0
Endothelial cell PECAM1 3.961 0.00e+0 0.00e+0
Endothelial cell IGFBP7 3.913 0.00e+0 0.00e+0
Endothelial cell CDH5 3.891 0.00e+0 0.00e+0
Endothelial cell KDR 3.872 0.00e+0 0.00e+0
Endothelial cell ADGRL4 3.863 0.00e+0 0.00e+0
Endothelial cell SPARCL1 3.750 0.00e+0 0.00e+0
Endothelial cell HSPG2 3.728 0.00e+0 0.00e+0
Endothelial cell ESAM 3.603 0.00e+0 0.00e+0
Endothelial cell RAMP3 3.567 0.00e+0 0.00e+0
Endothelial cell INSR 3.520 0.00e+0 0.00e+0
Endothelial cell LDB2 3.517 0.00e+0 0.00e+0
Endothelial cell ENG 3.472 0.00e+0 0.00e+0
Endothelial cell COL4A2 3.468 0.00e+0 0.00e+0
Endothelial cell RAMP2 3.363 0.00e+0 0.00e+0
Endothelial cell ACKR1 3.267 0.00e+0 0.00e+0
Endothelial cell RGS5 3.243 0.00e+0 0.00e+0
Endothelial cell COL15A1 3.168 0.00e+0 0.00e+0
Endothelial cell ADGRF5 3.115 0.00e+0 0.00e+0
Fibroblast MEG3 5.369 0.00e+0 0.00e+0
Fibroblast COL1A1 5.080 0.00e+0 0.00e+0
Fibroblast COL6A3 5.002 0.00e+0 0.00e+0
Fibroblast COL1A2 4.863 0.00e+0 0.00e+0
Fibroblast COL3A1 4.784 0.00e+0 0.00e+0
Fibroblast COL6A1 4.357 0.00e+0 0.00e+0
Fibroblast COL6A2 4.345 0.00e+0 0.00e+0
Fibroblast DCN 4.327 0.00e+0 0.00e+0
Fibroblast CDH11 4.093 0.00e+0 0.00e+0
Fibroblast THBS2 4.077 0.00e+0 0.00e+0
Fibroblast ACTA2 3.917 0.00e+0 0.00e+0
Fibroblast COL16A1 3.639 0.00e+0 0.00e+0
Fibroblast PDGFRA 3.633 0.00e+0 0.00e+0
Fibroblast LUM 3.609 0.00e+0 0.00e+0
Fibroblast C11orf96 3.566 0.00e+0 0.00e+0
Fibroblast COL5A1 3.524 0.00e+0 0.00e+0
Fibroblast MMP2 3.287 0.00e+0 0.00e+0
Fibroblast COL11A1 3.280 0.00e+0 0.00e+0
Fibroblast FN1 3.264 0.00e+0 0.00e+0
Fibroblast THBS1 3.254 0.00e+0 0.00e+0
Fibroblast CARMN 3.250 0.00e+0 0.00e+0
Fibroblast COL8A1 3.231 0.00e+0 0.00e+0
Fibroblast VCAN 3.176 0.00e+0 0.00e+0
Fibroblast BGN 3.060 0.00e+0 0.00e+0
Fibroblast COL5A2 2.944 0.00e+0 0.00e+0
Mast cell TCF7 5.192 0.00e+0 0.00e+0
Mast cell CLEC4A 5.187 0.00e+0 0.00e+0
Mast cell CDH19 5.048 0.00e+0 0.00e+0
Mast cell Negative5 5.006 0.00e+0 0.00e+0
Mast cell RPS4Y1 4.989 0.00e+0 0.00e+0
Mast cell ADGRV1 4.930 0.00e+0 0.00e+0
Mast cell TNFSF14 4.786 0.00e+0 0.00e+0
Mast cell ACKR3 4.676 0.00e+0 0.00e+0
Mast cell ANGPT2 4.547 0.00e+0 0.00e+0
Mast cell BIRC3 4.445 0.00e+0 0.00e+0
Mast cell FHIT 4.381 0.00e+0 0.00e+0
Mast cell SMO 4.376 0.00e+0 0.00e+0
Mast cell NLRP1 4.287 0.00e+0 0.00e+0
Mast cell CEACAM1 4.285 0.00e+0 0.00e+0
Mast cell CD1C 4.235 0.00e+0 0.00e+0
Mast cell CCL11 4.225 0.00e+0 0.00e+0
Mast cell TLR2 4.185 0.00e+0 0.00e+0
Mast cell MYH11 4.174 0.00e+0 0.00e+0
Mast cell IL7R 4.137 0.00e+0 0.00e+0
Mast cell CSF1R 4.136 0.00e+0 0.00e+0
Mast cell HEY1 4.040 0.00e+0 0.00e+0
Mast cell ITGAM 3.991 0.00e+0 0.00e+0
Mast cell LINC01781 3.966 0.00e+0 0.00e+0
Mast cell MTOR 3.951 0.00e+0 0.00e+0
Mast cell CD3G 3.833 0.00e+0 0.00e+0
Macrophage APOE 4.980 0.00e+0 0.00e+0
Macrophage C1QC 4.784 0.00e+0 0.00e+0
Macrophage LYZ 4.714 0.00e+0 0.00e+0
Macrophage CD163 4.673 0.00e+0 0.00e+0
Macrophage C1QB 4.476 0.00e+0 0.00e+0
Macrophage MSR1 4.433 0.00e+0 0.00e+0
Macrophage SPP1 4.402 0.00e+0 0.00e+0
Macrophage MS4A6A 4.285 0.00e+0 0.00e+0
Macrophage C1QA 4.063 0.00e+0 0.00e+0
Macrophage APOC1 3.978 0.00e+0 0.00e+0
Macrophage CD68 3.775 0.00e+0 0.00e+0
Macrophage FCER1G 3.503 0.00e+0 0.00e+0
Macrophage SLCO2B1 3.483 0.00e+0 0.00e+0
Macrophage SRGN 3.470 0.00e+0 0.00e+0
Macrophage RGS1 3.393 0.00e+0 0.00e+0
Macrophage MS4A4A 3.380 0.00e+0 0.00e+0
Macrophage OLR1 3.356 0.00e+0 0.00e+0
Macrophage TYROBP 3.352 0.00e+0 0.00e+0
Macrophage CD14 3.344 0.00e+0 0.00e+0
Macrophage CSF1R 3.336 0.00e+0 0.00e+0
Macrophage ITGAX 3.240 0.00e+0 0.00e+0
Macrophage FCGBP 3.119 0.00e+0 0.00e+0
Macrophage ITGB2 3.099 0.00e+0 0.00e+0
Macrophage GPNMB 3.053 0.00e+0 0.00e+0
Macrophage HLA-DPA1 2.997 0.00e+0 0.00e+0
ILC/T lineage cell CXCL13 4.762 0.00e+0 0.00e+0
ILC/T lineage cell CCL5 4.252 0.00e+0 0.00e+0
ILC/T lineage cell CD2 3.905 0.00e+0 0.00e+0
ILC/T lineage cell IKZF3 3.793 0.00e+0 0.00e+0
ILC/T lineage cell CD3D 3.730 0.00e+0 0.00e+0
ILC/T lineage cell IL7R 3.717 0.00e+0 0.00e+0
ILC/T lineage cell CCL4/L1/L2 3.458 0.00e+0 0.00e+0
ILC/T lineage cell CD52 3.200 0.00e+0 0.00e+0
ILC/T lineage cell NKG7 3.090 0.00e+0 0.00e+0
ILC/T lineage cell IL2RG 3.086 0.00e+0 0.00e+0
ILC/T lineage cell CD69 3.082 0.00e+0 0.00e+0
ILC/T lineage cell TIGIT 3.079 0.00e+0 0.00e+0
ILC/T lineage cell ETS1 3.049 0.00e+0 0.00e+0
ILC/T lineage cell PTPRCAP 3.024 0.00e+0 0.00e+0
ILC/T lineage cell GZMA 3.024 0.00e+0 0.00e+0
ILC/T lineage cell PRF1 3.004 0.00e+0 0.00e+0
ILC/T lineage cell ITGAL 3.004 0.00e+0 0.00e+0
ILC/T lineage cell ITK 2.998 0.00e+0 0.00e+0
ILC/T lineage cell GZMK 2.996 0.00e+0 0.00e+0
ILC/T lineage cell CD8A 2.985 0.00e+0 0.00e+0
ILC/T lineage cell CD3E 2.982 0.00e+0 0.00e+0
ILC/T lineage cell RAC2 2.976 0.00e+0 0.00e+0
ILC/T lineage cell IL32 2.953 0.00e+0 0.00e+0
ILC/T lineage cell IL2RB 2.945 0.00e+0 0.00e+0
ILC/T lineage cell GZMB 2.917 0.00e+0 0.00e+0
ILC lineage cell GNLY 4.550 0.00e+0 0.00e+0
ILC lineage cell CCL4 4.040 0.00e+0 0.00e+0
ILC lineage cell CCL4L2 3.625 0.00e+0 0.00e+0
ILC lineage cell NKG7 3.499 0.00e+0 0.00e+0
ILC lineage cell CCL5 3.401 0.00e+0 0.00e+0
ILC lineage cell KLRK1 3.325 0.00e+0 0.00e+0
ILC lineage cell IL2RB 3.263 0.00e+0 0.00e+0
ILC lineage cell GZMA 3.208 0.00e+0 0.00e+0
ILC lineage cell GZMK 2.918 0.00e+0 0.00e+0
ILC lineage cell CD52 2.696 0.00e+0 0.00e+0
ILC lineage cell STAT4 2.660 0.00e+0 0.00e+0
ILC lineage cell PTPRC 2.655 0.00e+0 0.00e+0
ILC lineage cell CD2 2.589 0.00e+0 0.00e+0
ILC lineage cell GZMB 2.569 0.00e+0 0.00e+0
ILC lineage cell CD69 2.547 0.00e+0 0.00e+0
ILC lineage cell ITGAL 2.465 0.00e+0 0.00e+0
ILC lineage cell ITGAE 2.402 0.00e+0 0.00e+0
ILC lineage cell IL2RG 2.362 0.00e+0 0.00e+0
ILC lineage cell PRF1 2.355 0.00e+0 0.00e+0
ILC lineage cell FYB1 2.321 0.00e+0 0.00e+0
ILC lineage cell ITK 2.315 0.00e+0 0.00e+0
ILC lineage cell CD3E 2.283 0.00e+0 0.00e+0
ILC lineage cell CTSW 2.281 0.00e+0 0.00e+0
ILC lineage cell CST7 2.279 0.00e+0 0.00e+0
ILC lineage cell GZMH 2.254 0.00e+0 0.00e+0
Tumor/Malignant cell IGF2 3.624 0.00e+0 0.00e+0
Tumor/Malignant cell CLU 3.508 0.00e+0 0.00e+0
Tumor/Malignant cell SLPI 3.074 0.00e+0 0.00e+0
Tumor/Malignant cell CD24 3.074 0.00e+0 0.00e+0
Tumor/Malignant cell KRT7 3.057 0.00e+0 0.00e+0
Tumor/Malignant cell EPCAM 3.016 0.00e+0 0.00e+0
Tumor/Malignant cell KRT8 3.001 0.00e+0 0.00e+0
Tumor/Malignant cell CLDN4 2.992 0.00e+0 0.00e+0
Tumor/Malignant cell SPINK1 2.955 0.00e+0 0.00e+0
Tumor/Malignant cell KRT19 2.847 0.00e+0 0.00e+0
Tumor/Malignant cell KRT18 2.787 0.00e+0 0.00e+0
Tumor/Malignant cell FGG 2.747 0.00e+0 0.00e+0
Tumor/Malignant cell DDR1 2.676 0.00e+0 0.00e+0
Tumor/Malignant cell ITGB8 2.578 0.00e+0 0.00e+0
Tumor/Malignant cell MECOM 2.444 0.00e+0 0.00e+0
Tumor/Malignant cell ERBB3 2.424 0.00e+0 0.00e+0
Tumor/Malignant cell NDRG1 2.358 0.00e+0 0.00e+0
Tumor/Malignant cell ESR1 2.279 0.00e+0 0.00e+0
Tumor/Malignant cell TTR 2.279 0.00e+0 0.00e+0
Tumor/Malignant cell CD9 2.275 0.00e+0 0.00e+0
Tumor/Malignant cell TACSTD2 2.261 0.00e+0 0.00e+0
Tumor/Malignant cell BMP7 2.254 0.00e+0 0.00e+0
Tumor/Malignant cell NPR1 2.221 0.00e+0 0.00e+0
Tumor/Malignant cell S100A6 2.110 0.00e+0 0.00e+0
Tumor/Malignant cell GSTP1 2.074 0.00e+0 0.00e+0
T cell CD8A 2.946 0.00e+0 0.00e+0
T cell CCL5 2.829 0.00e+0 0.00e+0
T cell CD2 2.730 0.00e+0 0.00e+0
T cell IL2RB 2.585 0.00e+0 0.00e+0
T cell KLRK1 2.578 0.00e+0 0.00e+0
T cell CXCL13 2.506 0.00e+0 0.00e+0
T cell GZMA 2.493 0.00e+0 0.00e+0
T cell CTLA4 2.488 0.00e+0 0.00e+0
T cell IL7R 2.449 0.00e+0 0.00e+0
T cell CD52 2.448 0.00e+0 0.00e+0
T cell GZMK 2.407 0.00e+0 0.00e+0
T cell GZMB 2.401 0.00e+0 0.00e+0
T cell PTPRC 2.390 0.00e+0 0.00e+0
T cell ITGAL 2.357 0.00e+0 0.00e+0
T cell IL2RG 2.337 0.00e+0 0.00e+0
T cell CD3D 2.303 0.00e+0 0.00e+0
T cell STAT4 2.274 0.00e+0 0.00e+0
T cell ITK 2.254 0.00e+0 0.00e+0
T cell CD3E 2.228 0.00e+0 0.00e+0
T cell CD69 2.227 0.00e+0 0.00e+0
T cell FYB1 2.159 0.00e+0 0.00e+0
T cell TIGIT 2.150 0.00e+0 0.00e+0
T cell CST7 2.048 0.00e+0 0.00e+0
T cell CD53 2.031 0.00e+0 0.00e+0
T cell ETS1 2.030 0.00e+0 0.00e+0