HGSC_39179931 · Xenium

HGSC_39179931 · HGSC_39179931__Xenium

Xenium Spatial transcriptomics Curated Tiered
Features

Cell-ontology markers

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Features tested
280
Label tier
cell_type_tier_3
Marker output
535 rows
QC
QC passed
Seurat FindAllMarkers, one curated cell-ontology label versus all others. Effect size is logFC; significance is BH FDR.
Cell ontology Feature logFC FDR p value
ILC lineage cell GNLY 7.457 0.00e+0 0.00e+0
ILC lineage cell KLRC1 5.631 0.00e+0 0.00e+0
ILC lineage cell KLRD1 5.580 0.00e+0 0.00e+0
ILC lineage cell PRF1 5.130 0.00e+0 0.00e+0
ILC lineage cell NKG7 4.931 0.00e+0 0.00e+0
ILC lineage cell KLRB1 4.663 0.00e+0 0.00e+0
ILC lineage cell CD247 4.579 0.00e+0 0.00e+0
ILC lineage cell CCL5 4.359 0.00e+0 0.00e+0
ILC lineage cell GZMA 3.914 0.00e+0 0.00e+0
ILC lineage cell KLRF1 3.618 0.00e+0 0.00e+0
ILC lineage cell CD69 3.030 0.00e+0 0.00e+0
ILC lineage cell DUSP2 2.740 0.00e+0 0.00e+0
ILC lineage cell IL2RG 2.734 0.00e+0 0.00e+0
ILC lineage cell PTPRC 2.668 0.00e+0 0.00e+0
ILC lineage cell GATA3 2.507 0.00e+0 0.00e+0
ILC lineage cell TIGIT 2.312 0.00e+0 0.00e+0
ILC lineage cell CYTIP 2.015 0.00e+0 0.00e+0
ILC lineage cell CD3E 2.011 0.00e+0 0.00e+0
ILC lineage cell HAVCR2 1.844 0.00e+0 0.00e+0
ILC lineage cell CXCR4 1.796 0.00e+0 0.00e+0
ILC lineage cell ADGRE5 1.655 0.00e+0 0.00e+0
ILC lineage cell FCER1G 0.887 3.53e-254 1.73e-254
ILC lineage cell ITGAX 1.622 1.05e-234 5.36e-235
ILC lineage cell CD8A 2.001 4.41e-168 2.35e-168
ILC lineage cell IL7R 1.871 3.15e-156 1.75e-156
Mast cell CPA3 7.170 0.00e+0 0.00e+0
Mast cell TPSAB1 6.053 0.00e+0 0.00e+0
Mast cell CTSG 5.371 0.00e+0 0.00e+0
Mast cell KIT 5.145 0.00e+0 0.00e+0
Mast cell ANKRD30A 3.539 4.44e-260 2.50e-261
Mast cell S100A8 2.571 5.86e-236 3.95e-237
Mast cell CEACAM8 3.823 6.26e-174 4.92e-175
Mast cell KRT6B 3.229 8.61e-160 7.74e-161
Mast cell TAC1 3.265 7.82e-146 7.90e-147
Mast cell MMP12 3.503 5.38e-142 6.05e-143
Mast cell TCL1A 2.894 2.92e-139 3.61e-140
Mast cell CD274 2.745 2.28e-125 3.07e-126
Mast cell MUC6 2.766 1.67e-121 2.44e-122
Mast cell CLEC9A 3.210 1.80e-121 2.84e-122
Mast cell MYO5B 2.501 3.39e-120 5.72e-121
Mast cell KLRC1 2.376 8.79e-116 1.58e-116
Mast cell ADIPOQ 2.409 2.08e-112 3.98e-113
Mast cell MYBPC1 2.958 1.08e-109 2.18e-110
Mast cell CD69 2.648 1.12e-86 2.39e-87
Mast cell ADH1B 1.697 6.28e-85 1.41e-85
Mast cell LYZ 0.715 2.56e-63 6.03e-64
Mast cell CCL8 1.921 4.30e-63 1.06e-63
Mast cell MRC1 1.226 5.20e-61 1.34e-61
Mast cell ITGAX 1.006 2.69e-58 7.26e-59
Mast cell ANKRD29 1.834 4.17e-57 1.17e-57
B cell MZB1 6.761 0.00e+0 0.00e+0
B cell CD79A 6.397 0.00e+0 0.00e+0
B cell MS4A1 5.876 0.00e+0 0.00e+0
B cell TENT5C 5.772 0.00e+0 0.00e+0
B cell SLAMF7 5.016 0.00e+0 0.00e+0
B cell CD19 4.439 0.00e+0 0.00e+0
B cell PRDM1 4.235 0.00e+0 0.00e+0
B cell BANK1 3.913 0.00e+0 0.00e+0
B cell TNFRSF17 3.907 0.00e+0 0.00e+0
B cell ERN1 3.733 0.00e+0 0.00e+0
B cell CD27 3.512 0.00e+0 0.00e+0
B cell SEC11C 3.406 0.00e+0 0.00e+0
B cell CD79B 3.358 0.00e+0 0.00e+0
B cell RAB30 3.324 0.00e+0 0.00e+0
B cell CYTIP 3.236 0.00e+0 0.00e+0
B cell RHOH 3.003 0.00e+0 0.00e+0
B cell DUSP5 2.784 0.00e+0 0.00e+0
B cell CXCR4 2.775 0.00e+0 0.00e+0
B cell PECAM1 2.514 0.00e+0 0.00e+0
B cell SLAMF1 2.505 0.00e+0 0.00e+0
B cell SEC24A 2.282 0.00e+0 0.00e+0
B cell SELL 2.197 0.00e+0 0.00e+0
B cell IL2RG 1.934 0.00e+0 0.00e+0
B cell SMAP2 1.912 0.00e+0 0.00e+0
B cell VOPP1 1.743 0.00e+0 0.00e+0
Endothelial cell VWF 6.483 0.00e+0 0.00e+0
Endothelial cell CLEC14A 6.407 0.00e+0 0.00e+0
Endothelial cell EGFL7 6.288 0.00e+0 0.00e+0
Endothelial cell ANGPT2 5.632 0.00e+0 0.00e+0
Endothelial cell ESM1 5.245 0.00e+0 0.00e+0
Endothelial cell AVPR1A 5.243 0.00e+0 0.00e+0
Endothelial cell RAMP2 5.078 0.00e+0 0.00e+0
Endothelial cell AQP1 4.991 0.00e+0 0.00e+0
Endothelial cell MYH11 4.934 0.00e+0 0.00e+0
Endothelial cell KDR 4.663 0.00e+0 0.00e+0
Endothelial cell HOXD9 4.549 0.00e+0 0.00e+0
Endothelial cell NOSTRIN 4.538 0.00e+0 0.00e+0
Endothelial cell CD93 4.536 0.00e+0 0.00e+0
Endothelial cell MMRN2 3.997 0.00e+0 0.00e+0
Endothelial cell PECAM1 3.949 0.00e+0 0.00e+0
Endothelial cell PDGFRB 3.875 0.00e+0 0.00e+0
Endothelial cell CAVIN2 3.851 0.00e+0 0.00e+0
Endothelial cell CAV1 3.770 0.00e+0 0.00e+0
Endothelial cell IL3RA 3.769 0.00e+0 0.00e+0
Endothelial cell STC1 3.767 0.00e+0 0.00e+0
Endothelial cell FOXC2 3.310 0.00e+0 0.00e+0
Endothelial cell ACTA2 2.473 0.00e+0 0.00e+0
Endothelial cell CRISPLD2 2.337 0.00e+0 0.00e+0
Endothelial cell ANKRD29 2.241 0.00e+0 0.00e+0
Endothelial cell ZEB1 2.158 0.00e+0 0.00e+0
Fibroblast PDGFRA 5.408 0.00e+0 0.00e+0
Fibroblast SFRP4 4.700 0.00e+0 0.00e+0
Fibroblast MMP2 3.574 0.00e+0 0.00e+0
Fibroblast GJB2 3.505 0.00e+0 0.00e+0
Fibroblast LUM 3.390 0.00e+0 0.00e+0
Fibroblast CCDC80 3.358 0.00e+0 0.00e+0
Fibroblast POSTN 3.253 0.00e+0 0.00e+0
Fibroblast CRISPLD2 3.159 0.00e+0 0.00e+0
Fibroblast PGR 3.020 0.00e+0 0.00e+0
Fibroblast FSTL3 2.955 0.00e+0 0.00e+0
Fibroblast FBLN1 2.928 0.00e+0 0.00e+0
Fibroblast RUNX1 2.886 0.00e+0 0.00e+0
Fibroblast ALDH1A3 2.885 0.00e+0 0.00e+0
Fibroblast CXCL12 2.748 0.00e+0 0.00e+0
Fibroblast ZEB1 2.708 0.00e+0 0.00e+0
Fibroblast DST 2.546 0.00e+0 0.00e+0
Fibroblast ACTA2 2.532 0.00e+0 0.00e+0
Fibroblast TCF4 2.322 0.00e+0 0.00e+0
Fibroblast HOXD8 2.283 0.00e+0 0.00e+0
Fibroblast PDGFRB 2.239 0.00e+0 0.00e+0
Fibroblast PIM1 2.216 0.00e+0 0.00e+0
Fibroblast SVIL 2.186 0.00e+0 0.00e+0
Fibroblast SFRP1 1.977 0.00e+0 0.00e+0
Fibroblast IGF1 1.977 0.00e+0 0.00e+0
Fibroblast ANKRD29 1.974 0.00e+0 0.00e+0
Macrophage ITGAX 4.848 0.00e+0 0.00e+0
Macrophage CD163 4.689 0.00e+0 0.00e+0
Macrophage APOC1 4.158 0.00e+0 0.00e+0
Macrophage C1QC 4.099 0.00e+0 0.00e+0
Macrophage C1QA 4.055 0.00e+0 0.00e+0
Macrophage FCER1G 4.000 0.00e+0 0.00e+0
Macrophage ITGAM 3.984 0.00e+0 0.00e+0
Macrophage CD14 3.920 0.00e+0 0.00e+0
Macrophage CD68 3.825 0.00e+0 0.00e+0
Macrophage FCGR3A 3.728 0.00e+0 0.00e+0
Macrophage MRC1 3.639 0.00e+0 0.00e+0
Macrophage LYZ 3.534 0.00e+0 0.00e+0
Macrophage HAVCR2 3.501 0.00e+0 0.00e+0
Macrophage MNDA 3.494 0.00e+0 0.00e+0
Macrophage IGSF6 3.424 0.00e+0 0.00e+0
Macrophage FGL2 3.390 0.00e+0 0.00e+0
Macrophage CD86 3.322 0.00e+0 0.00e+0
Macrophage AIF1 3.319 0.00e+0 0.00e+0
Macrophage CD4 3.093 0.00e+0 0.00e+0
Macrophage GPR183 3.082 0.00e+0 0.00e+0
Macrophage S100A8 3.038 0.00e+0 0.00e+0
Macrophage CD80 2.812 0.00e+0 0.00e+0
Macrophage CX3CR1 2.649 0.00e+0 0.00e+0
Macrophage CD83 2.565 0.00e+0 0.00e+0
Macrophage LY86 2.441 0.00e+0 0.00e+0
T cell CTLA4 4.686 0.00e+0 0.00e+0
T cell TRAC 4.634 0.00e+0 0.00e+0
T cell IL7R 4.570 0.00e+0 0.00e+0
T cell CD3E 4.454 0.00e+0 0.00e+0
T cell GZMA 4.397 0.00e+0 0.00e+0
T cell CD8A 4.205 0.00e+0 0.00e+0
T cell CD247 4.108 0.00e+0 0.00e+0
T cell CCL5 3.975 0.00e+0 0.00e+0
T cell FOXP3 3.962 0.00e+0 0.00e+0
T cell TIGIT 3.940 0.00e+0 0.00e+0
T cell CD3G 3.862 0.00e+0 0.00e+0
T cell KLRB1 3.782 0.00e+0 0.00e+0
T cell CD69 3.658 0.00e+0 0.00e+0
T cell NKG7 3.647 0.00e+0 0.00e+0
T cell IL2RG 3.503 0.00e+0 0.00e+0
T cell PRF1 3.485 0.00e+0 0.00e+0
T cell PTPRC 3.138 0.00e+0 0.00e+0
T cell CCR7 3.102 0.00e+0 0.00e+0
T cell GATA3 2.916 0.00e+0 0.00e+0
T cell SLAMF1 2.867 0.00e+0 0.00e+0
T cell LTB 2.854 0.00e+0 0.00e+0
T cell RHOH 2.807 0.00e+0 0.00e+0
T cell CYTIP 2.793 0.00e+0 0.00e+0
T cell CD27 2.597 0.00e+0 0.00e+0
T cell LAG3 2.440 0.00e+0 0.00e+0
ILC/T lineage cell CD8A 4.305 0.00e+0 0.00e+0
ILC/T lineage cell GZMA 3.713 0.00e+0 0.00e+0
ILC/T lineage cell CCL5 3.584 0.00e+0 0.00e+0
ILC/T lineage cell CD3E 3.447 0.00e+0 0.00e+0
ILC/T lineage cell NKG7 3.431 0.00e+0 0.00e+0
ILC/T lineage cell TRAC 3.412 0.00e+0 0.00e+0
ILC/T lineage cell CD3G 3.016 0.00e+0 0.00e+0
ILC/T lineage cell PRF1 2.949 0.00e+0 0.00e+0
ILC/T lineage cell IL7R 2.937 0.00e+0 0.00e+0
ILC/T lineage cell CTLA4 2.928 0.00e+0 0.00e+0
ILC/T lineage cell CD247 2.891 0.00e+0 0.00e+0
ILC/T lineage cell TIGIT 2.883 0.00e+0 0.00e+0
ILC/T lineage cell CD69 2.831 0.00e+0 0.00e+0
ILC/T lineage cell IL2RG 2.801 0.00e+0 0.00e+0
ILC/T lineage cell PTPRC 2.684 0.00e+0 0.00e+0
ILC/T lineage cell KLRB1 2.528 0.00e+0 0.00e+0
ILC/T lineage cell KLRD1 2.411 0.00e+0 0.00e+0
ILC/T lineage cell LAG3 2.356 0.00e+0 0.00e+0
ILC/T lineage cell CYTIP 2.249 0.00e+0 0.00e+0
ILC/T lineage cell RHOH 2.099 0.00e+0 0.00e+0
ILC/T lineage cell CCR7 2.044 0.00e+0 0.00e+0
ILC/T lineage cell GATA3 2.009 0.00e+0 0.00e+0
ILC/T lineage cell CD27 1.965 0.00e+0 0.00e+0
ILC/T lineage cell KLRC1 1.857 0.00e+0 0.00e+0
ILC/T lineage cell SLAMF1 1.832 0.00e+0 0.00e+0
Tumor/Malignant cell KRT7 3.629 0.00e+0 0.00e+0
Tumor/Malignant cell EPCAM 3.392 0.00e+0 0.00e+0
Tumor/Malignant cell TACSTD2 3.313 0.00e+0 0.00e+0
Tumor/Malignant cell SOX17 3.307 0.00e+0 0.00e+0
Tumor/Malignant cell KLF5 3.167 0.00e+0 0.00e+0
Tumor/Malignant cell CDH1 3.153 0.00e+0 0.00e+0
Tumor/Malignant cell DSP 3.011 0.00e+0 0.00e+0
Tumor/Malignant cell SCGB2A1 2.850 0.00e+0 0.00e+0
Tumor/Malignant cell C6orf132 2.538 0.00e+0 0.00e+0
Tumor/Malignant cell TFAP2A 2.517 0.00e+0 0.00e+0
Tumor/Malignant cell KRT23 2.467 0.00e+0 0.00e+0
Tumor/Malignant cell KRT5 2.445 0.00e+0 0.00e+0
Tumor/Malignant cell HMGA1 2.436 0.00e+0 0.00e+0
Tumor/Malignant cell PIGR 2.359 0.00e+0 0.00e+0
Tumor/Malignant cell ESR1 2.346 0.00e+0 0.00e+0
Tumor/Malignant cell KRT8 2.316 0.00e+0 0.00e+0
Tumor/Malignant cell MLPH 2.254 0.00e+0 0.00e+0
Tumor/Malignant cell JUP 2.244 0.00e+0 0.00e+0
Tumor/Malignant cell CD9 2.215 0.00e+0 0.00e+0
Tumor/Malignant cell S100A14 2.209 0.00e+0 0.00e+0
Tumor/Malignant cell HOOK2 2.174 0.00e+0 0.00e+0
Tumor/Malignant cell CCND1 2.173 0.00e+0 0.00e+0
Tumor/Malignant cell DMKN 2.163 0.00e+0 0.00e+0
Tumor/Malignant cell DSC2 2.149 0.00e+0 0.00e+0
Tumor/Malignant cell CENPF 2.041 0.00e+0 0.00e+0