Network Topology

Ready samples 7,465

Dataset Organ Disease state Technique Modality Cell ontology tier ?

Compare Choose one valid graph-level topology metric.

Comparison group ? Metric ?

Modularity (Tier 1), compared across disease state × organ

24 groups · 7465 samples · 79 datasets ?

Q modularity: Homogeneous <0.15 · Weakly structured 0.15-0.35 · Highly modular >=0.35 r assortativity: Highly dispersed <=-0.15 · Weakly mixed -0.15--0.02 · Neutral -0.02-0.02 · Weakly segregated 0.02-0.15 · Highly compartmentalized >=0.15

Modularity (Tier 1), compared across disease state × organ

Group	Organ	Samples	Datasets	Median	Rank	Min	Q1	Q3
Healthy/control × Small intestine	39	1	0.31	0.206	0.279	0.334	0.408	0.303
Healthy/control × Skin	128	3	0.299	0.023	0.263	0.334	0.444	0.29
Primary cancer × Uterus/Cervix	7	4	0.296	0.109	0.124	0.311	0.385	0.237
Primary cancer × Adrenal gland	24	1	0.255	0.001	0.141	0.309	0.394	0.224
Healthy/control × Large intestine	75	5	0.232	0.011	0.134	0.321	0.414	0.22
Primary cancer × Lymphoid tissue	2,226	9	0.222	0	0.131	0.297	0.467	0.213
Metastatic cancer × Brain	121	2	0.222	0.005	0.145	0.287	0.463	0.218
Primary cancer × Head and neck	292	3	0.215	0.008	0.137	0.301	0.437	0.218
Primary cancer × Lung	800	10	0.212	0	0.144	0.274	0.5	0.209
Non-cancer disease × Lung	35	1	0.209	0.074	0.153	0.319	0.395	0.229
Metastatic cancer × Peritoneum	66	2	0.204	0.026	0.129	0.283	0.41	0.207
Healthy/control × Musculoskeletal	1	1	0.2	0.2	0.2	0.2	0.2	0.2
Primary cancer × Large intestine	684	15	0.184	0	0.103	0.271	0.441	0.189
Primary cancer × Breast	1,000	14	0.172	0	0.1	0.235	0.421	0.174
Metastatic cancer × Skin	5	1	0.165	0.011	0.105	0.184	0.196	0.132
Primary cancer × Ovary	156	12	0.153	0	0.078	0.234	0.407	0.161
Healthy/control × Spinal cord	2	1	0.147	0.132	0.14	0.155	0.163	0.147
Healthy/control × Breast	97	4	0.136	0	0.012	0.257	0.422	0.145
Primary cancer × Prostate	4	3	0.135	0.092	0.102	0.171	0.188	0.138
Non-cancer disease × Skin	4	1	0.132	0.081	0.113	0.15	0.183	0.132
Non-cancer disease × Large intestine	93	3	0.109	0.002	0.03	0.206	0.354	0.131
Primary cancer × Bone marrow	62	4	0.104	0.049	0.088	0.124	0.253	0.109
Healthy/control × Bone marrow	27	2	0.103	0	0	0.122	0.178	0.071
Primary cancer × Kidney	3	2	0.1	0.084	0.092	0.15	0.2	0.128